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JuryProf. Carine MICHIELS (UNamur), ChairProf. Anne-Catherine HEUSKIN (UNamur), SecretaryProf. Stéphane LUCAS (UNamur)Dr. Rudi LABARBE (IBA)Prof. Joao SECO (German Cancer Research Center)Prof. Simon GALAS (University of Montpellier)AbstractRadiotherapy is one of the most widely used treatments for cancer and plays a central role in modern oncology. While technological advances have greatly improved the precision of radiation delivery, damage to healthy tissues surrounding the tumor remains a major limitation. In recent years, an innovative approach known as FLASH radiotherapy has attracted considerable attention. Unlike conventional radiotherapy, FLASH delivers the therapeutic radiation dose within a fraction of a second using ultra-high dose rates. A growing body of evidence suggests that this approach may reduce radiation-induced side effects in healthy tissues while maintaining the ability to control tumours. However, the biological mechanisms responsible for this protective effect remain poorly understood.This thesis addressed two key challenges in FLASH research. The first was the development and characterization of an experimental platform capable of generating ultra-high dose rate irradiations using the ALTAÏS accelerator at the University of Namur. This work involved designing irradiation systems, validating beam dosimetry, and establishing robust experimental protocols to ensure accurate and reproducible exposure conditions. The second objective was to introduce a new biological model for FLASH investigations: the microscopic nematode Caenorhabditis elegans (C. elegans). This organism offers several advantages, including a short life cycle, ease of handling, low cost, and the conservation of many fundamental biological processes shared with higher organisms. These characteristics make it an attractive complementary model for studying radiation responses and exploring the mechanisms underlying the FLASH effect.This thesis demonstrated the suitability of C. elegans as a model for investigating biological responses to ultra-high dose rate irradiation. Studies of developmental and neurobiological endpoints across multiple irradiation conditions highlighted its potential for mechanistic FLASH research. Together, these findings provide valuable tools to advance our understanding of the FLASH effect. More broadly, they contribute to the development of safer radiotherapy strategies aimed at reducing treatment-related toxicity and improving patient quality of life.

Jointly founded by the University of Namur and UCLouvain, the spin-off Intercept Bio aims to take a new step forward in the prevention of viral respiratory infections. Stemming from research conducted by the teams of Professor Stéphane Vincent at the UNamur Bio-Organic Chemistry Laboratory and Professor David Alsteens at the Louvain Institute of Biomolecular Science and Technology at UCLouvain, and a researcher at the WEL Research Institute, the start-up is developing a nasal spray designed to act right at the entry point for respiratory viruses: the nasal passages.

Researchers at ULiège and UNamur are developing a new electrochromic material: MoWOx.

An international team of researchers has just published an article in the prestigious journal Light: Science & Applications (LSA) from the Nature group.  The teams led by Professors Michaël Lobet and Alexandre Mayer (University of Namur) collaborated with the team led by Professor Shanhui Fan, one of the leading experts in the field, from the prestigious Stanford University in California (USA).  The result: an article entitled ‘Twist-Induced Beam Steering and Blazing Effects in Photonic Crystal Devices’, or the study of beam deflection by twisting in photonic crystal devices.  Come on, let's twist light again at UNamur! 

This is a great recognition of research at UNamur: three Marie Skłodowska-Curie Doctoral Networks (DN) projects have just been awarded, with a key contribution from researchers in Namur! The first, in chemistry, involves Professor Stéphane Vincent; the second, focused on ecosystem resilience, involves Professor Frédérik de Laender; and the third, in the field of photonics, benefits from the expertise of FNRS-qualified researcher Michaël Lobet.

Michaël Lobet, professor in the Department of Physics, and André Fuzfa, astrophysicist and professor in the Department of Mathematics at UNamur, have just been awarded a grant from the Wernaers Fund to develop an original scientific project: the design of a comic strip that will explore all the fascinating facets of energy. Aimed at a "student" audience, it will weave the link between science and science fiction, and will be produced thanks to the invaluable pencil strokes of illustrator Jean-Marc Dubois.

Since its launch in December 2022, ChatGPT, the chatbot developed by OpenAI, an artificial intelligence company co-founded by Elon Musk, has continued to elicit astonished comments and concerned questions, including: is the human brain still useful?

Faced with the ecological crisis and soaring energy prices, the energy transition has become an undeniable emergency. Every day, at UNamur, researchers from a wide range of fields - geology, chemistry, physics, computer science - are thinking about innovative ways of dealing with this perilous future.

Professors, lecturers, assistants and pedagogical experts from UNamur took part in a workshop to evaluate and critique the use of ChatGPT in university courses. Numerous examples of practices including AI in teaching were carried out in the courses offered at UNamur this term. A survey was also carried out among Block 1 students on their use and knowledge of artificial intelligence.

On January 23 and 24, 2025, UNamur experts were present at the SETT (School Education Transformation Technology) trade show for its sixth edition. A must-attend event for digital education in the Wallonia-Brussels Federation, dedicated to principals, teachers and technical-pedagogical advisors.

An international team of physicists led by Dr Michaël Lobet, lecturer at UNamur, re-examines the foundations of quantum physics from the point of view of momentum in the prestigious journal Nature Light Science & Applications. The researchers investigated what happens when this momentum is reduced to zero. Some interesting things happen! Explanations.

Let's go and discover the qualified researchers of UNamur, winners of the funding granted by the FNRS in 2022. Today, we meet Michaël Lobet, currently a lecturer at UNamur, who will begin his new mandate as a qualified FNRS researcher at the NISM Institute next fall. The subject of his research: twisted optics for the manipulation of slow photons or how to create light traps. Explanations.