Learning outcomes

By the end of this module, students should be able

  • to follow a scientific approach and

  • to communicate with their peers using appropriate language.

Goals

This course unit aims to:

  • Present research projects from their design to their publication in a scientific journal
  • Develop students’ creativity and critical thinking
  • Train students in scientific communication


Content

The course comprises seminars delivered by external guest speakers and the course co-leaders, as well as discussions on the following topics :

  1. the clathrin-independent endocytosis of cargo molecules

  2. the exocytosis of the metalloproteinase MT1-MMP in breast cancer cells

  3. the recycling of proteins from endosomes to the plasma membrane

  4. the sensing and the adaptation of cellular structures to mechanical forces

  5. the intracellular transport of proteins along the microtubules

  6. the organelle-based genome photoprotection

Table of contents

Dr. Isabelle HAMER (UNamur): Intracellular transport of the matrix metalloproteinase MT1-MMP in breast cancer cells.

Prof. Henri-François RENARD (UNamur): Unconventional clathrin-independent endocytosis.

Prof. Francesco BASCHIERI (Medical University of Innsbruck): Plasticity of cell adhesions in cancer cell migration. 

Prof. Maud MARTIN (ULB) : Secreting at the right place : regulation of the molecular machinery responsible for transporting constitutive secretion vesicles. 

Dr. Cédric Delevoye, Directeur de Recherche, Inserm, Insitut Necker Enfants Malades, Paris: Organelle-based strategy of genome photoprotection

Dr. Cédric Blouin, Chargé de Recherche Inserm, Institut Curie, Paris : Caveolae mechanics in cellular functions and disease.

 

Teaching methods

This teaching unit is a module in which most of the lessons are delivered in the form of seminars, mainly by guest researchers from outside the university. In these cases, the presentations will be preceded by a short introduction by the students and followed by a Question and Answer session.

Several lectures will also be delivered by the module co-coordinators. During these sessions, students will need to work together to consider different experimental approaches to answer a biological question.


This teaching unit implies an active participation of the students.

Assessment method

Continuous assessment based on:

  • Introduction to a speaker’s research work presented to the group (by pairs of students)

  • Active participation in seminars (questions asked and answers given by students)

  • Design of a mini research project and its presentation to the group (by pairs of students)


Sources, references and any support material

PubMed, slides, videos (available on Webcampus).

Language of instruction

English
Training Study programme Block Credits Mandatory
Master in Biochemistry and Molecular and Cell Biology Finalité approfondie 1 3 Yes
Master in Biochemistry and Molecular and Cell Biology Finalité spécialisée 1 3 Yes
Master in Biomedical Sciences Filière en recherche fondamentale et préclinique 1 3 Yes
Master in Biomedical Sciences Standard 1 3 No