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Bringing a new drug to market, particularly when it is intended to treat a pediatric or orphan disease, is a journey fraught with pitfalls. The ERAMET project, coordinated by Professor Flora Musuamba Tshinanu, aims to overhaul the assessment procedures, so that regulatory agencies can take innovative technologies into account and thus make more informed choices.

Hepatocellular carcinoma is the most common primary liver cancer. Unfortunately, this tumor still has a high mortality rate due to the lack of effective treatments for its most advanced or poorly localized forms. As part of a partnership with the CHU UCL Namur - site de Godinne and with the support of Roche Belgium, researchers in the Department of Biomedical Sciences are trying to understand why liver tumor cells are so resistant to treatment, and to identify therapeutic alternatives to better target them.

This is a significant honor for two members of the UNamur School of Medicine: Professor Charlotte Beaudart, who heads the "clinical research" track of the Master’s program in biomedical sciences, and Professor Jonathan Douxfils (School of Medicine, URPC – NARILIS) have just joined the College of Young Researchers of the Royal Academy of Medicine of Belgium.

In late November, the Mont-Saint-Guibert-based company Cellistic® donated equipment it no longer used to UNamur. By enabling the university to give this equipment a second life, Cellistic is making an important gesture in support of the development of university research.

Since September 2023, Marc Hennequart, Professor of Biochemistry and Cell Biology at UNamur, has been conducting groundbreaking research into pancreatic cancer. His team, based at the Faculty of Medicine and the Institut Narilis, studies the early stages of oncogenesis (the process of transforming a normal cell into a cancerous one) to better understand the metabolic changes behind this particularly aggressive cancer.

Beautiful victory for Margaux Mignolet, a researcher at the Faculty of Medicine's Unité de Recherche en Physiologie Moléculaire (URPhyM), who wins 1st prize in the Belgian inter-university final of the Ma thèse en 180 secondes (MT180) competition. Her research? To better understand the mechanisms of antibodies active in cases of long COVID. The second prize in this national competition was also won by a candidate from Namur. It was Petra Manja, from the Unité de Recherche en biologie des micro-organismes (URBM), Department of Biology, Faculty of Science, and is pursuing a thesis aimed at understanding resistance mechanisms in the bacterium E. coli. Both are also researchers at the NARILIS Institute.

On Saturday, April 18, 2026, Vice-Rector for Research Benoît Champagne and Professor Anne-Catherine Heuskin, a Télévie project sponsor, represented the UNamur community on the set of the Télévie gala. On this occasion, they presented a check for 20,000 euros to support this FRS-FNRS initiative, which raises funds to finance numerous research projects at universities in the Wallonia-Brussels Federation, with one goal: to improve treatments for this disease, which now affects nearly 80,000 new patients and claims nearly 30,000 lives each year in Belgium. 

The Covid-19 pandemic is a human tragedy that has caused millions of deaths worldwide and put our entire society under great strain. But it has also been a tremendous collective moment for many UNamur scientists, whose research continues in an attempt to better understand this disease and its consequences.

At UNamur, parchments are much more than objects of curiosity: they are at the heart of an interdisciplinary scientific adventure. Starting with historical sciences and conservation, the research has gradually incorporated the disciplines of physics, biology, chemistry, and archaeology.  This convergence has given rise to research in heritage sciences, driving innovative projects such as Marine Appart's doctoral work, supervised by Professor Olivier Deparis. This research has now been recognized with a publication in the prestigious journal Heritage Science (Nature Publishing Group).

Supported by the SPW Research’s Win4SpinOff program and led by the University of Liège through its Mass Spectrometry Laboratory (MSLab, Faculty of Science) and the University of Namur through its Laboratory of Molecular Cancer Biology, (NARILIS, LBMC, Faculty of Medicine), the VENOM2 project explores the potential of peptides derived from animal venoms to develop new diagnostic and therapeutic solutions in oncology.

AbstractPopulation aging is accompanied by an increase in the prevalence of neurodegenerative diseases, including tauopathies. This family of diseases, which includes Alzheimer’s disease, is characterized by the mislocalization, hyperphosphorylation, and accumulation of the tau protein in a pathological form, leading to neuronal dysfunction and ultimately neuronal death within the central nervous system. Numerous studies conducted in humans and in various animal models have demonstrated an association between repeated head trauma and the development of a specific tauopathy, chronic traumatic encephalopathy. This progressive neurodegenerative disease is attributed to repeated exposure to impacts to the head that generate acceleration-deceleration forces in the brain.Although the brain and spinal cord share many cellular and tissue characteristics, the consequences of spinal cord trauma on the development of tauopathies remain largely unexplored. To investigate this question, a new mouse model of repeated mild spinal cord trauma was developed in the PS19 mouse, a transgenic model of tauopathy that replicates several characteristics of frontotemporal dementia. Two low-intensity spinal cord contusions (30 kDynes), administered three weeks apart, were performed at two months of age to assess their impact on the long-term progression of the disease.Although these injuries induce neither immediate clinical deficits, nor detectable tissue lesions, nor neuronal loss, they elicit a marked glial response as well as neuronal and axonal damage, as evidenced by increased circulating concentrations of neurofilament light chains. Longitudinal follow-up of the animals revealed an earlier onset of motor and sensory deficits, associated with an accelerated decline in their overall health.In the short term (3.5 months), no worsening of tauopathy was observed. However, at 6.5 months of age, a significant increase in the density of hyperphosphorylated forms of tau, detected by the pTau(Ser202/Thr205) and pTau(Ser422) antibodies, was observed near the epicenter of the lesion in the contusion-injured animals. By 9 months, this exacerbation of the pathology had spread along the rostral-caudal axis, between spinal cord segments C2 and C7, as well as to the thalamus. Although spinal cord injuries did not alter Tau protein aggregation, in vitro analyses showed that the insoluble protein fraction extracted from the spinal cord of contusion-injured animals possessed greater recruitment capacity.Although no direct causal link could be established, histological, biochemical, and transcriptomic analyses suggest the involvement of microglia, type I interferon signaling, and the p38 MAP kinase pathway in stimulating Tau hyperphosphorylation.Taken together, these results highlight a previously largely underestimated role of mild spinal cord injuries as a factor promoting the development and progression of tauopathies. They also reinforce existing literature suggesting that neuroinflammation—and more specifically, microglial activation and type I interferon signaling—contributes to the progression of these diseases. Finally, this study underscores the importance of long-term follow-up for individuals exposed to spinal cord injuries—even mild ones—due to the potential increased risk of developing neurodegenerative diseases involving the Tau protein.JuryProf. Pascal KIENLEN-CAMPARD (UCLouvain)Prof. Karelle LEROY (ULB)Prof. Aurélie LADANG (ULiège)Prof. Charles NICAISE (UNamur)Prof. Patsy RENARD (UNamur), ChairProf. Laurence RIS (UMons)

Stanford University has published a prestigious ranking that highlights the most influential researchers in a wide range of scientific fields. The list, based on bibliographic criteria, aims to provide a standardized means of identifying the world's scientific leaders. It is one criterion among others for assessing the quality of scientific research. Twelve researchers from the University of Namur are among them!