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Researchers from UNamur's Departments of Biology and Physics have conducted a scientific experiment to assess the radioresistance of the common black ant Lasius niger. The results of their work have just been published in the Belgian scientific journal Belgian Journal of Zoology. The Namur-based scientists demonstrate a level of resistance far superior to that of humans. Their spontaneous approach also demonstrates a lesser-known approach to scientific research.

The TineaDiag project is a research project run by UNamur and ULiège with funding from the SPW Research Win²WAL program. It tackles dermatophytoses, skin infections responsible for ringworm, which can affect both humans and animals. The aim? To identify, in dermatophytes, precise cellular markers in order to detect them with sensitivity and certainty, and thus identify infections caused by antifungal-resistant strains.

Since September 2023, Marc Hennequart, Professor of Biochemistry and Cell Biology at UNamur, has been conducting groundbreaking research into pancreatic cancer. His team, based at the Faculty of Medicine and the Institut Narilis, studies the early stages of oncogenesis (the process of transforming a normal cell into a cancerous one) to better understand the metabolic changes behind this particularly aggressive cancer.

The F.R.S.-FNRS has just published the results of its various 2024 calls. Equipment calls, research credits and projects, FRIA doctoral grants and Mandant d'Impulsion Scientifique (MIS), there are many instruments to support fundamental research. Find out more about UNamur's results.

In late November, the Mont-Saint-Guibert-based company Cellistic® donated equipment it no longer used to UNamur. By enabling the university to give this equipment a second life, Cellistic is making an important gesture in support of the development of university research.

Thematic sessionsThe day will be organized in two thematic sessions:Cancer metabolismNew advances in cancer therapyInvited speakersProf. Rebecca FITZGERALD, Early Cancer Institute, University of Cambridge, UKDr. Sébastien DUTERTRE, IBMM, University of Montpellier, FranceProf. Sarah-Maria FENDT, Laboratory of Cellular Metabolism and Metabolic Regulation, VIB-KU Leuven, BelgiumDr. Arnaud BLOMME, Laboratory of Metabolic Regulation, GIGA Institute, University of Liège, Belgium Call for communicationsYoung researchers are invited to submit abstracts for oral communications and posters. All topics related to the field of cancer research are welcome. The deadline for abstract submission is April 1, 2025. Organizing committeeProf. Jean-Pierre Gillet - UNamur, NARILIS, Laboratory of Molecular Cancer BiologyProf. Marc Hennequart - UNamur, NARILIS, Laboratory of Cancer metabolismProf. Marielle Boonen - UNamur, NARILIS, Laboratory of Intracellular Trafficking BiologyProf. Benjamin Beck - ULB, IRIBHMProf. Lionel D'Hondt - CHU UCL Namur, Department of Oncology More info

The colloquium will be held on Tuesday, April 15 and Wednesday, April 16, 2025, at the University of Namur (Belgium). Proposals for papers (programmatic title and abstract of 500 signs, followed by a biobibliography) can be sent by November 15, 2024 to Jean-Benoit.Gabriel@unamur.be and Denis.Saint-Amand@unamur.be.

Abstract Radiotherapy is a cornerstone of cancer treatment and is currently administered to approximately half of all cancer patients. However, the cytotoxic effects of ionizing radiation on normal tissues represent a major limitation, as they restrict the dose that can be safely delivered to patients and, consequently, reduce the likelihood of effective tumor control. In this context, delivering radiation at ultra-high dose rates (UHDR, > 40 Gy/s) is gaining increasing attention due to its potential to spare healthy tissues surrounding the tumor and to prevent radiation-induced side effects, as compared to conventional dose rates (CONV, on the order of Gy/min).The mechanism underlying this protective effect-termed the FLASH effect-remains elusive, driving intensive research to elucidate the biological processes triggered by this type of irradiation.In vitro models offer a valuable tool to support this research, allowing for the efficient screening of various beam parameters and biological responses in a time- and cost-effective manner. In this study, multicellular tumor spheroids and normal cells were exposed to proton irradiation at UHDR to evaluate its efficacy in controlling tumor growth and its cytotoxic impact on healthy tissues, respectively.We report that UHDR and CONV irradiation induced a comparable growth delay in 3D tumor spheroids, suggesting similar efficacy in tumor control. In normal cells, both dose rates induced similar levels of senescence; however, UHDR irradiation led to lower apoptosis induction at clinically relevant doses and early time points post-irradiation.Taken together, these findings further highlight the potential of UHDR irradiation to modulate the response of normal tissues while maintaining comparable tumor control.JuryProf. Thomas BALLIGAND (UNamur), PresidentProf. Stéphane LUCAS (UNamur), SecretaryProf. Carine MICHIELS (UNamur)Dr Sébastien PENNINCKX (Hôpital Universitaire de Bruxelles)Prof. Cristian FERNANDEZ (University of Bern)Dr Rudi LABARBE (IBA)

The discovery of nuclear energy marked a turning point in human history. Today, alongside debates about its role in energy production and its destructive potential, nuclear energy continues to be used in a wide range of fields, such as medical research and cancer treatments. At UNamur, nuclear energy is thus at the heart of the work of biologists, physicists, and art historians.