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EMBO Courses and Workshops are selected for their excellent scientific quality and timelines, provision of good networking activities for all participants and speaker gender diversity (at least 40% of speakers must be from the underrepresented gender). Organisers are encouraged to implement measures to make the meeting environmentally more sustainable.Upon registration - More info and registration on the EMBO website.

Characterization of trehalase from Acyrthosiphon pisum for the design of new insecticides SummaryAphids are major pests in agriculture, causing direct damage to plants and acting as vectors for phytopathogenic viruses. Conventional insecticides are widely used to control them, but their toxicity and efficacy pose problems in terms of the environment, human health and the emergence of resistance to these compounds. New alternatives are therefore needed, such as biological control using predators or parasitoids. However, these methods are not always economically viable on a large scale. As part of this thesis, another approach is being explored which involves developing new insecticides targeting the biochemical functions of aphids.The project aims to discover new inhibitors of trehalase, an enzyme essential for insect energy metabolism. Inhibition of this enzyme could disrupt vital insect functions without affecting mammals. This research involved several stages: the purification and complete characterization of trehalase from Acyrthosiphon pisum (the model for this study), the in vivo, in vitro and in silico analysis of commercial inhibitors on this enzyme, before moving on to the search for new inhibitors. Two points of integrated insect management were explored, biological and chemical control.The biological side saw the study of a strain of Streptomyces naturally producing trehalase-inhibiting metabolites, notably validamycin A, a molecule recognized in the literature as one of the best inhibitors, but not applicable as an insecticide. Other molecules appear to have interesting features, but we have not been able to isolate and characterize them.The chemical side has enabled us to create a pharmacophore hypothesis based on experimental results on molecules obtained by virtual screening. Although these molecules are not usable as insecticides as they stand, this hypothesis provides a better understanding of trehalase inhibitors in general and can be used to refine future analyses. JuryProf. Jean-Yves MATROULE (UNamur), presidentDr Catherine MICHAUX (UNamur), promoter and secretaryProf. Frédéric FRANCIS (ULiège), co-promoterProf. André MATAGNE (ULiège)Dr Rudy CAPARROS (ULiège)Dr Morgan HANS (Biocidal)

His long-term collaboration with Dr. Aniruddha Chatterjee recently resulted in the first collaborative framework agreement between the University of Otago and UNamur, as well as an international Erasmus+ (EU) credit mobility funding this scientific mission. Frédéric Silvestre deepened his understanding of the advanced DNA methylation techniques employed by Dr. Chatterjee's team, including their bioinformatics workflows and innovative approach to epigenetic editing. He has given several seminars presenting LEAP's research on mangrove rivulus and turquoise molefish. He also presented at the Australasian Epigenetic Alliance conference and had the opportunity to explore potential new collaborations with other departments, including zoology, sustainable development, chemistry and marine sciences.

Quentin Willot (Biology) has just joined URBE for a two-year post-doctoral position (Marie Sklodowska-Curie Action, supervisor: Alice Dennis) on a project called ChillAnts. This project focuses on the study of adaptation to extreme temperatures in holarctic (trans-Beringian) ant species, from a physiological, ecological and evolutionary point of view. Quentin will present a more technical aspect of his work (Thermal Death Time Curve Modelling).

With oral and poster presentations by ILEE affiliates. Students and young researchers are particularly invited to present their research and practice their presentation skills in English. The day is also important for ILEE members as it enables them to keep abreast of ongoing projects in different disciplines and to foster collaboration.At the end of the day, the annual general meeting of all members will take place with a summary of the past year's activities and achievements.We are honored to announce that Arnaud Péters, PhD in history and founder of sites_H, will be the keynote speaker!

High-Sensitivity Birefringence Mapping Using Near-Circularly Polarized Light I will describe several techniques for mapping a two-dimensional birefringence distribution, which can be classified according to the optical schemes and principles of work:Illumination geometry (transmitted light/reflected light)Image acquisition (sequential acquisition/simultaneous acquisition)Polarization control (electrically controlled variable retardance/mechanical rotation).This classification facilitates a comparative analysis of the capabilities and limitations in these methods for birefringence characterization. Polychromatic polarizing microscopy (PPM) provides unique capabilities to alternative methods. It leverages vector interference to generate vivid, full-spectrum colors at extremely low retardances, down to < 10 nm. PPM is a significant departure from conventional polarizing microscopes that rely on Newton interference, which requires retardances above 400 nm for color formation. Furthermore, PPM's color output directly reflects the orientation of the birefringent material, a feature absent in conventional microscopy where color is solely determined by retardance.Joint seminar of ILEE & NISM!The seminar is open to external people too, no need to register. More info

Deadlines Opening of abstract submissions and registrations: September 15, 2025Deadline to submit indicative title and summary: November 30, 2025Deadline for final abstract submissions: May 1, 2026Early bird registration deadline: March 1, 2026 More information on the website