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Take part in our open morning Given the works in the rue de Bruxelles and the renovation of part of the University parking lots, we invite you to use public transport whenever possible (train or bus) to reach Namur. UNamur boasts an ideal location, in the heart of the city just a five-minute walk from the TEC and SNCB train stations.If you're coming by car, take a look at the parking map provided. Look forward to seeing you on Saturday, June 29!

Initiated in 1969 by Pullmann and Del Re, the congress is an annual meeting to promote collaboration and friendship between Latin-speaking theoretical chemists. In its early years, European researchers were the main contributors. Subsequently, the Latin American community has made a major contribution, with the emergence of teams whose international reputation now extends far beyond our own community.We are delighted to be holding this meeting at the University of Namur, 55 years after the first CHITEL was organised in Paris, France. We are sure that this 2024 edition will once again be an opportunity to take advantage of the good humour and dynamism of Latin to encourage, develop and strengthen scientific exchanges.We look forward to welcoming you at the University of Namur,The CHITEL 2024 Local Organising Committee. Website

EMBO Courses and Workshops are selected for their excellent scientific quality and timelines, provision of good networking activities for all participants and speaker gender diversity (at least 40% of speakers must be from the underrepresented gender). Organisers are encouraged to implement measures to make the meeting environmentally more sustainable.Upon registration - More info and registration on the EMBO website.

On Thursday May 30, for our last Chill&Sciences of the season, Candy Sonvaux and Alexis Coyette, mathematics researchers, invite you to discover the mathematics where the movements of the planets and the spread of viruses intertwine until they impact our society.Chill&Science: enriching encountersWith nearly 20 years' experience of scientific cafés, the Confluent des Savoirs has set up a new concept of scientific encounters. The Chill&Sciences are a unique opportunity for the public to come and discuss and ask questions of experts on research topics related to current affairs and citizen issues.Come and enjoy the unique, relaxed atmosphere of Quai22. Researchers and experts from the seven faculties of the University of Namur will present their research and discuss with you over a drink (or two, but never without exaggeration).In practiceThe meetings are open to everyone aged 16 and over. Evenings are limited to around 20 people to ensure a relaxed atmosphere and to facilitate discussions. Meetings take place if a minimum of 10 people are registered. Except in exceptional circumstances, meetings take place every 2 months at the University of Namur's cultural space, Quai22, located at n°22 Rue du Séminaire.Tarif Participation in a Chill&Sciences costs 5€. A discounted annual pass is available. Please note: preferential rate for students (discount code: PromoCDS).The booking fee includes a drink* (soft or beer), a snack (chips and cookies) and management fees linked to the organization Unless cancelled by us, bookings are non-refundable. (*additional drinks will be available upon electronic payment.)

Title of the dissertation: Ion implantation in Low-E coatings Low-emissivity (Low-E) coating technology revolutionizes glass applications for windows, offering high optical transparency while reducing heat transfer. They consist of a silver-based thin film deposited on a glass panel by physical vapor deposition. However, these coatings are fragile and must be placed inside a double-glazing cavity where an inert gas resides. Otherwise, they can be easily degraded by bad atmospheric conditions.The thesis approach is to combine low-E technology with a post-treatment of ion implantation. The research question driving this thesis is: how does ion implantation enhance the durability of low-E coatings containing silver?The experiments conducted during the thesis show that implantation indeed increases the coating resistance while having a small impact on its color. However, the treatment degrades the thermal insulation properties. Hence, a series of hypotheses are formulated based on the literature to explain and control this behavior.A deeper investigation shows that implantation impacts the silver nanostructure. First by dewetting the film which allows reorganization into larger crystallites, second by forcing silver mixing at its interface through ballistic ejections. These two phenomena increase the toughness of the silver interface by interlocking effects. However, dewetting has also been linked to thermal insulation properties degradation. Nonetheless, it was shown that using light gas implantation limits the destructive effect (dewetting) while still inducing good durability (due to interface mixing).. Jury Prof. Julien COLAUX (UNamur), presidentProf. Stéphane LUCAS (UNamur), promoter and secretaryDr Amory JACQUES (Service Public de Wallonie)Dr Philippe ROQUINY (AGC Glass Europe)Prof. Rony SNYDERS (University of Mons)

Program 8:50 | Welcome, registration, and poster setup9:20 | Welcome speechFirst morning session 9:30 | Vladimir N. Uversky - University of South Florida, USA - "Dancing protein clouds: strange biology and chaotic physics of intrinsically disordered proteins" 10:15 | Marie Skepö - Lunds Universitet, Sweden - "Structural and conformation properties of IDPs: computer simulations in combination with experiments" 11:00 | Coffee breakSecond morning session11:30 | Peter Tompa - Vrije Universiteit Brussel, Belgium - "Fuzzy interactions of IDPs driving biomolecular condensation"12:15 | Sonia Longhi - Aix-Marseille Université, France - "Intrinsic disorder, phase transitions, and fibril formation by the Henipavirus V and W proteins"13:00 | Lunch and poster sessionAfternoon session14:30 | Sigrid Milles - Leibniz-Forschungsinstitut für Molekulare Pharmakologie, Germany - "Intrinsically disordered proteins in endocytosis: an NMR and single molecule fluorescence perspective"15:15 | Jean-François Collet - Université Catholique de Louvain, Belgium - "How disorder controls the transport of lipoproteins in the cell envelope of Gram-negative bacteria" 16:00 | Closing speech16:10 | Networking Beer Time at "Le Chapitre"VenueUniversity of Namur, auditorium Pedro Arrupe (PA02), rue de Bruxelles, 65-67 - 5000 Namur (#21 on the campus map) Download the programme (PDF) Download the campus map Registration guidelines Registration feeStudents (PhD students included): 25 €Seniors: 40 €Payment - Bank transferPayable before 6 December on the account:Name: Université de Namur - ASBLIBAN: BE10 2500 0740 2704BIC: GEBABEBBPlease mention your name/CPO4136330 /e-mail in the payment communication. Abstract guidelines Send us your abstract before 6 December by email: pdid.meeting@unamur.beFormat: Word document, maximum 1 page A4, Times New Roman  Registration All deadlines (registration, payment, abstracts) : 6 December 2024

SummaryIn 2025, machine learning continues to revolutionize various scientific fields, with major implications in physics, particularly photonics. The integration of advanced machine learning algorithms has enabled significant advances in the design and control of photonic systems, improving their efficiency and performance. These advances are essential for the development of communication, imaging and quantum computing technologies. However, physics research presents many challenges that go beyond simple performance measurements: identifying patterns and building analytical models is often just as crucial.In this thesis, we apply computational intelligence tools, in particular heuristic optimization and neural networks, to develop data-driven approaches to solving various tasks in physics. Although data-centric, our approach remains rooted in physics, always seeking to understand the physical phenomena underlying the algorithms. The results of this thesis cover a wide range of applications, from the design of complex metasurfaces and diffraction gratings to the analysis and interpretation of spectral data. We have also successfully developed an optimizer capable of learning and adapting to the problems encountered, particularly in physics. This key tool in our arsenal outperforms state-of-the-art methods in our applications. In particular, it has enabled the design of a coronagraphic phase plate for exoplanet imaging, with a performance 25% better than the best previous solutions.We have also designed a compact, all-dielectric beam deflection device, operating efficiently for all polarizations, reaching a maximum efficiency of 90%. Starting from a purely data-driven design, we were able to extract and validate an analytical model based on the behavior of an echelle lattice, providing a physical understanding of its operation. In addition to simulation-based tasks, we also processed experimental data, developing an animal origin classifier for scrolls, capable of distinguishing three animal species with 90% accuracy. This tool offers a non-invasive method for conservators and historians wishing to analyze fragile historical materials.Jury members Prof. Michaël LOBET (UNamur), PresidentProf. Alexandre MAYER (UNamur), SecretaryDr. Charlotte BEAUTHIER (CENAREO)Prof. Benoît FRENAY (UNamur)Prof. Olivier DEPARIS (UNamur)Prof. Denis LANGEVIN (Université de Clermont Auvergne)Prof. Hai Son NGUYEN (Ecole Centrale de Lyon)

Essay topic Essays on the Empirical Analysis of Crypto-Assets: Market Efficiency, Peg Failures, and Financial Flights Composition of the Jury Promoter: Prof. Jean-Yves Gnabo (UNamur)Other jury members: Prof. Sophie Béreau (UNamur)Prof. Kris Boudt (UGent)Prof. Sarah Bouraga (EM Normandie)Prof. Jérôme Lahaye (Fordham University)Jury president: Prof. Corentin Burnay (UNamur)

Abstract Primarily described as an alarmone, secondary messenger (p)ppGpp, when accumulated, binds to many targets involved in DNA replication, translation, and transcription. In the asymmetrically-dividing a-proteobacterium Caulobacter crescentus, (p)ppGpp has been shown to strongly impact cell cycle progression and differentiation, promoting the non-replicating G1/swarmer phase. Mutations in the major subunits of transcriptional complex, b or b' subunits, were able to display the (p)ppGpp-related phenotypes even in the absence of the alarmone. We identified that the transcriptional holo-enzyme, RNA polymerase (RNAP) is a primary target of (p)ppGpp in C. crescentus. Furthermore, mutations that inactivate (p)ppGpp binding to RNAP annihilated the (p)ppGpp-related phenotypes and phenocopied a (p)ppGpp0 strain. Our RNAseq analysis further elucidated the changes in the transcriptional landscape of C. crescentus cells displaying different (p)ppGpp levels and expressing RNAP mutants. Since the DNA replication initiation protein DnaA is required to exit the G1 phase, we observed that it was significantly less abundant in cells accumulating (p)ppGpp. We further explored its proteolysis under the influence of (p)ppGpp. Our work suggests that (p)ppGpp regulates cell cycle and differentiation in C. crescentus by reprogramming transcription and triggering proteolytic degradation of key cell cycle regulators by yet unknown mechanisms. In Part II, we identified two σ factors belonging to the ECF family that might be involved in this (p)ppGpp-accompanied phenotypes. In Part III, we propose an overlapping role of the ω subunit, RpoZ, and the heat shock subunit, RpoH, in carbon metabolism.JuryProf. Gipsi LIMA MENDEZ (UNamur), PresidentProf Régis HALLEZ (UNamur), SecretaryDr Emanuele BIONDI (CNRS-Université Paris-Saclay)Prof. Justine COLLIER (University of Lausanne)Dr Marie DELABY (Université de Montréal)

Abstract Estrogens originating from human and animal excretion, as well as from anthropogenic sources such as cosmetics, plastics, pesticides, detergents, and pharmaceuticals, are among the most concerning endocrine-disrupting compounds in aquatic environments due to their potent estrogenic activity. While their effects on fish reproduction are well documented, their impact on development, particularly metamorphosis, remains poorly studied. This hormonal transition, mainly controlled by the thyroid axis, is essential for the shift from the larval to the juvenile stage in teleosts.The effects of two contraceptive estrogens on zebrafish (Danio rerio) metamorphosis were evaluated: 17α-ethinylestradiol (EE2), a synthetic reference estrogen, and estetrol (E4), a natural estrogen recently introduced in a new combined oral contraceptive formulation. Continuous exposure from fertilization to the end of metamorphosis allowed the assessment of morphological changes, disruptions of the thyroid axis, and modifications of additional molecular pathways potentially involved in metamorphic regulation.EE2 induced significant delays and disturbances in metamorphosis, affecting both internal and external morphological traits, confirming its role as an endocrine disruptor of concern. In contrast, E4 did not cause any detectable morphological alterations even at concentrations far exceeding those expected in the environment, indicating a limited ecotoxicological risk. Molecular analyses showed that EE2 strongly affected thyroid signaling and energy metabolism during metamorphosis, whereas E4 induced only minor transcriptional and proteomic changes.This study provides the first evidence that EE2 can disrupt zebrafish metamorphosis and highlights the importance of including this developmental stage in ecotoxicological assessments. The results also suggest a larger environmental safety margin for E4, although further research is needed to clarify the mechanisms linking estrogen exposure to metamorphic regulation.JuryProf. Frederik DE LAENDER (UNamur), PresidentProf. Patrick KESTEMONT (UNamur), SecretaryDr. Sébastien BAEKELANDT (UNamur)Dr. Valérie CORNET (UNamur)Prof. Jean-Baptiste FINI (Muséum National d'Histoire Naturelle, Paris)Dr. Marc MULLER (ULiège)Prof. Veerle DARRAS (KULeuven)

Abstract This work demonstrates that polymer-coated gold nanoparticles can function not only as radiosensitizers but also as agents for macrophage reprogramming. Specifically, we show that these nanoparticles can repolarize tumor-associated macrophages from the immunosuppressive M2 phenotype to the pro-inflammatory M1 phenotype-a process further enhanced by clinically relevant doses of X-ray radiation. Among the four nanoparticle formulations tested, 50 nm PVP-coated gold nanoparticles were particularly effective in promoting macrophage repolarization and reducing pancreatic cancer cell viability in co-culture, both with and without radiation. These findings highlight a promising strategy to enhance the efficacy of cancer radiotherapy. Jury Prof. Julien COLAUX (UNamur), ChairmanProf. Anne-Catherine HEUSKIN (UNamur), SecretaryProf. Carine MICHIELS (UNamur)Prof. Henri-François RENARD (UNamur)Prof. Michel MOUTSCHEN (ULiège)Dr Dimitri STANICKI (UMons)Prof. Devika CHITHRANI (University of Victoria)

Welcome to the 1ʳᵉ MG-ERC conference This conference, linked to the research themes of the Chemistry Department, aims to bring together around 100 researchers working in the fields of heteroatom chemistry, coordination chemistry, catalysis, and inorganic chemistry. It represents a real novelty in Belgium in terms of the areas covered, and will enable participants to discover new concepts, ideas and trends in these recent areas of research in chemistry. Here is the list of speakers, who are world experts in their fieldsDr. Daniël Broere (Utrecht University, Netherlands)Prof. Agnieszka Nowak-Król (Universität Würzburg, Germany)Dr. Antoine Simonneau (Université Paul-Sabatier, Toulouse, France)Prof. Dr. Sebastian Riedel (Freie Universität, Berlin, Germany)Dr. Arnaud Voituriez (Université Paris-Saclay, France)Prof. Dr. Alessandro Bismuto (Universität Bonn, Germany)Dr. Christian Hering-Junghans (Leibniz-Institut für Katalyse, Germany)Prof. Connie Lu (Universität Bonn, Germany)Prof. Simon Aldridge (University of Oxford, UK)Dr. Ghenwa Bouhadir (Université Paul-Sabatier, Toulouse, France)Prof. Dr. Viktoria Däschlein (Universität Bonn, Germany)Prof. Viktoria Däschlein-Gessner (Ruhr-University of Bochum, Germany)Dr. Jennifer A. Garden (University of Edinburgh, UK)Prof. Muriel Hissler (Université de Rennes, France)Prof. Jean-François Paquin (Université de Laval, Canada) More information and registration