julien delbrouck

PhD student

Tel: +32 (0)81 72 41 11
julien.delbrouck@unamur.be

Bibliographical sketch:

Julien A. Delbrouck graduated from the University of Namur with a first-class honors degree in Chemistry Sciences in 2014. He worked on a multistep synthesis of C-nucleosides during his Master’s studies at Namur. He then moved to Basel for a three months internship in the pharmaceutical and early development department of Hoffmann La Roche where he worked in the field of infectious diseases.

Since october 2014, He is working toward a PhD degree under the supervision of Prof. Stéphane Vincent (UNamur), with research in the field of bio-organic chemistry. The two main project  are related to: A) the debenzylative cycloetherification reaction applied to multistep synthesis B) the preparation of new fluorinated substrates analogues of UGM, a key enzyme involved in the mycobacterium tuberculosis cell wall biosynthesis.

He obtained his PhD in November 20th, 2018.

Research activities:

- "Regioselective Synthesis of Difluorinated C‑Furanosides Involving a Debenzylative Cycloetherification" Org. Lett. 2019, 21, 14, 5562−5566.

- "Efficient and regioselective synthesis of γ-lactone glycosides through a novel debenzylative cyclization reaction" Chem. Commun. 2018, 54, 9845−9848.

- “Debenzylative Cycloetherification : An Overlooked key strategy for Complex Tetrahydrofuran Synthesis” Chem. Eur. J. 2016, 22, 9456−9476.

Book chapter:
- “Fluorine in Life Sciences. Pharmaceuticals, Medical Diagnostics and Agrochemicals" Chapter 6: Fluorosugars as inhibitors of bacterial enzymes, 2018.