Remind students of atomic structure and present some applications of physics in biomedicine: X-rays, spectrometry, fluorescence, flow cytometry, medical imaging, radiation protection.
Explain the principles of proteomic analysis of biological samples and cells, using mass spectrometry and flow cytometry respectively. Study and discuss some experimental applications.
Understand the principle of many advanced technologies and equipment.
Critique the advantages and limitations of these approaches.
Analyze the results of experiments carried out using these techniques/technologies in biomedical studies.
- reminder of atomic structure - applications : X rays, ionizing radiations, spectroscopy, MRI - experimental technologies : proteomics, mass spectrometry and flow cytometry -radioprotection
Part A-C Heuskin:
- atomic structure
- spectroscopy (emission, absorption)
- plate reader and immunofluorescence
- X rays and radioisotopes, interactions with matter
- imaging: principles, detectors and image reconstruction
- RMN and IRM
- radioprotection
Part Thierry Arnould :
- Flow cytometry, FACS and biological applications
- Proteomics, Mass spectrometry and biological applications
Part J-F Nisolle:
medical physics: principles of conventional radiology, computed tomography (CT), magnetic resonance imaging (MRI), ultrasound and PET-CT - notions of clinical radiation protection: radiological image formation and radiation protection, risk of small doses, which dose for which examination, practical procedures to follow
N/A
power point + notes taken by students
Written exam in three parts, with the final mark being the mathematical average of the three parts. In the event of overall failure (<10/20), the student MUST retake all parts of the course. The exam is closed-book.
In the event of serious failures (mark strictly below 7/20) in one or more of the 3 parts of this course, the lowest mark among the 3 parts will appear on the transcript.
The material covered by the assessment includes everything covered in the course.
YS Cordiolani : "radioprotection en milieu médical": Masson 2008 Review articles for mass spectrometry and cytometry related to medical use : given by the professor.
Syllabus
Slides and PPT supports.
| Training | Study programme | Block | Credits | Mandatory |
|---|---|---|---|---|
| Bachelor in Biomedical Sciences | Standard | 0 | 4 | |
| Bachelor in Biomedical Sciences | Standard | 2 | 4 |