The NISM institute brings together the research activities of the chemistry and physics departments at the University of Namur. Research at the NISM institute focuses on various topics in organic chemistry, physical chemistry, (nano)materials chemistry, surface science, optics and photonics, and solid-state physics, from both a theoretical and experimental perspective.
The institute's researchers have recognized expertise in the field of synthesis and functionalization of molecular systems and innovative materials, from 0 to 3 dimensions. They develop analytical and numerical modeling tools for the rational design of molecules and (nano)materials with specific architectures that confer functional end properties.
They draw on a range of advanced experimental techniques to study the chemical and physical properties of these systems at the micro- and nanometric scale. The research conducted at the institute falls within the field of both fundamental research, aimed at understanding and predicting the properties of structured matter, and applied research, aimed at developing functional materials and devices.
NISM's research areas are currently grouped into four clusters, whose boundaries are flexible, reflecting the transdisciplinary nature of the research topics and the collaborative dynamics between clusters.
Each cluster is represented by a permanent scientist and a non-permanent scientist who, together with the institute's president and vice president, form the institute's executive committee.
NISM research poles
Research at NISM is identified by four poles which highlight the main scientific activities carried out within the institute. Each pole is a well-defined structure with members, and is managed by the pole representative. The structuring of the pole does not prevent ongoing cooperation between them. Indeed, there is well-established interaction between the various poles, through joint projects, conferences, seminars, co-supervision of master's and doctoral theses, among others.
Spotlight
Agenda
Public Defense of a Doctoral Dissertation in Physical Sciences - Lucas Schoenauen
Development and Characterization of a UHDR Irradiation Station on ALTAÏS: C. elegans as a New, Powerful Model for FLASH Research
Jury
- Prof. Carine MICHIELS (UNamur), Chair
- Prof. Anne-Catherine HEUSKIN (UNamur), Secretary
- Prof. Stéphane LUCAS (UNamur)
- Dr. Rudi LABARBE (IBA)
- Prof. Joao SECO (German Cancer Research Center)
- Prof. Simon GALAS (University of Montpellier)
Abstract
Radiotherapy is one of the most widely used treatments for cancer and plays a central role in modern oncology. While technological advances have greatly improved the precision of radiation delivery, damage to healthy tissues surrounding the tumor remains a major limitation. In recent years, an innovative approach known as FLASH radiotherapy has attracted considerable attention. Unlike conventional radiotherapy, FLASH delivers the therapeutic radiation dose within a fraction of a second using ultra-high dose rates. A growing body of evidence suggests that this approach may reduce radiation-induced side effects in healthy tissues while maintaining the ability to control tumours. However, the biological mechanisms responsible for this protective effect remain poorly understood.
This thesis addressed two key challenges in FLASH research. The first was the development and characterization of an experimental platform capable of generating ultra-high dose rate irradiations using the ALTAÏS accelerator at the University of Namur. This work involved designing irradiation systems, validating beam dosimetry, and establishing robust experimental protocols to ensure accurate and reproducible exposure conditions. The second objective was to introduce a new biological model for FLASH investigations: the microscopic nematode Caenorhabditis elegans (C. elegans). This organism offers several advantages, including a short life cycle, ease of handling, low cost, and the conservation of many fundamental biological processes shared with higher organisms. These characteristics make it an attractive complementary model for studying radiation responses and exploring the mechanisms underlying the FLASH effect.
This thesis demonstrated the suitability of C. elegans as a model for investigating biological responses to ultra-high dose rate irradiation. Studies of developmental and neurobiological endpoints across multiple irradiation conditions highlighted its potential for mechanistic FLASH research. Together, these findings provide valuable tools to advance our understanding of the FLASH effect. More broadly, they contribute to the development of safer radiotherapy strategies aimed at reducing treatment-related toxicity and improving patient quality of life.
IBAF Conference 2026
Sixteen years after hosting the 2010 edition, UNamur is delighted to revive this scientific tradition and welcome the 11th edition of the Rencontres Ion Beam Applications Francophones (IBAF). This edition will be organized by scientists from the UNamur Physics Department who are active in the fields of materials science, biophysics, and interdisciplinary applications of ion beams.
The IBAF Meetings have been organized since 2003, every two years since 2008, by the Ion Beams Division of the French Vacuum Society (SFV), the oldest national vacuum society in the world, which celebrated its 80th anniversary in 2025.
As in previous editions, IBAF 2026 will offer a rich and varied program with guest lectures, oral and poster presentations, and technical sessions. All this will be complemented by an industrial presence to promote exchanges between research and innovation.
The conference will cover a wide range of topics, from ion beam instruments and techniques to the physics of ion-matter interactions, including the analysis and modification of materials, applications in the life sciences, earth and environmental sciences, and heritage sciences.