The HoMER team is working on the pharmacological modulation of the secretory pathway, specifically targeting the first major regulatory step in protein trafficking: the exit from the endoplasmic reticulum (ER) at the ER exit sites (ERES). The team is studying the effects of ERES on cellular homeostasis, as well as identifying new compounds capable of modulating protein trafficking.
Project Investigator (PI) | Alison Forrester
Alison Forrester is an FNRS Qualified Researcher, a NARC Fellow, and a researcher at the WEL Research Institute. Her HoMER (Homeostasis and Modulation of ERES) team is part of the URBC as well as NARILIS at the University of Namur.
View Alison Forrester’s profile in the UNamur directory.
The project members specialize in optical microscopy techniques for studying protein trafficking, particularly confocal microscopy and live-cell microscopy, including arrayed light-sheet microscopy.
The team works in a highly collaborative and interdisciplinary environment, combining cell biology, chemical biology, advanced microscopy, and image analysis to develop projects ranging from basic biology to translational research.